Stuff released between DNF being announced and now in no particular order:
Consoles
Neo Geo Pocket Color
Wonderswan
Dreamcast
Gameboy Advance and GBA SP
N-Gage
PSOne (this one may be a little unfair, but still-)
Playstation 2 and PSTwo
X-Box
Gamecube
Nintendo DS
Games
All the GTA games
Half-Life, it’s expansions, and any game using it’s engine
Fallout, Fallout 2, all other Infinity Engine games
Final Fantasies VII, VIII, IX, X, X-2 XI, Tactics, Tactics Advance, Crystal Chronicles, Origins, Anthology, Chronicles
All the Tomb Raider games except the first
Sonic Adventure, Adventure 2, Heroes, Advance 1, 2 and 3 and Sonic Collection
Legend of Zelda: Four Swords, Wind Waker, Ocarina of Time, Majora’s Mask, Link’s Awakening DX, Link to the Past GBA and the Oracle games
Daikatana
Unreal, Return to Castle Wolfenstein, Unreal Tournament, Unreal 2, UT2K3, UT2K4
Quakes 2 and 3
Any game using any of the above two serie’s engines
All the Thief games
All the Medal of Honour games
The Sims and all it’s myriad expansions
All Tony Hawk’s Pro Skater games
Metal Gear Solid 1, 2, Substance and 3
Warcraft III and it’s expansion
Many, many FIFA sports game, one for the SNES!
Might & Magic VI, VII, VIII and IX
Anarchy Online, Star Wars Galaxies, Lineage II, World of Warcraft, Ragnarok Online, and a whole asshat-full of MMORPGs
Romance of the Three Kingdoms VI, VII, VIII, IX, Dynasty Warriors 1-4, Samurai Warriors, Kessen 1 & 2, Dynasty Tactics 1 & 2, Mystic Heroes
Every Dance Dance Revolution game ever
Every US Pokemon game
Twenty Mega Man titles for various systems
AT LEAST thirty Star Wars titles.
Tron 2.0
Call of Duty and it’s expansion pack
Far Cry
Half-Life 2 and Counterstrike: Source
Doom 3
Many Working Designs games (WD are famous for taking a long time on their games) including Albert’s Oddysey, Magic Knight Rayearth, Raystorm, Elemental Gearbolt, Lunar: Silver Star Story, Lunar 2: Eternal Blue, Alundra, Arc the Lad Collection, Vanguard Bandits, Raycrisis, ThunderForce V, Silpheed and Gungriffon Blaze.
Halo 1 and 2
Thousands of other games including the entire back catalogues of the consoles list here.
Random
The Voyager 1 spacecraft has travelled approximately 2,348,783,105 miles since the announcement of Duke Nukem Forever.
The rovers Spirit and Opportunity went from proposal to successful landing on Mars within the timeframe of Duke Nukem Forever’s development.
The majority of the children who were entering high school the school year following Duke Nukem Forever’s announcemnt are now eligible to drink.
Over 5000 Americans have been killed in over 30 terrorist attacks since Duke Nukem Forever was announced (CONSPIRACY!)
The Human Genome Project was completed halfway between DNF’s development and now (five years after announcement).
PVPOnline, Penny Arcade, MegaTokyo and a few others went from being self-hosted gimmicky webcomics to million-reader businesses capable of sustaining their creators between DNF and now.
The Sega Saturn, Dreamcast, 3DO and Sega CD consoles were all discountinued at various times between DNF’s announcement and now.
Old Videogaming systems became a viable collector’s market (games and systems started to become valued at higher amounts then they had originally cost among antiques collectors as well as gamers).